Speaker
Description
The Cognitive Function Instrument (CFI) is a self-report and partner-report questionnaire designed to quantify subjectively perceived cognitive difficulties in older adults. The aim of this study is to investigate whether it is possible to determine a cut-off score that can distinguish individuals with and without subjective cognitive decline (SCD).
Thirty subjects (14 females; age = 71.8 ± 5.11) were neuropsychologically tested and then divided into two groups according to the presence of subjective cognitive decline: SCD and noSCD. They showed no significant differences in terms of number, gender, age or education. All participants were administered both versions of the CFI questionnaire. Due to the small sample size and the non-normally distributed data, comparisons were made using the non-parametric Mann-Whitney U-test.
We found that the two groups differed significantly in both CFI reports (self: p = 0.011; partner: p = 0.001). The Receiver Operating Characteristic (ROC) was calculated to measure the discriminatory ability of the instrument to identify SCD. We observed good discrimination for the area under the curve of self-report (AUC: 0.77) and very good discrimination for partner-report (AUC: 0.85). With a specificity of 0.87 and a sensitivity of 0.8, it was therefore possible to determine a cut-off value for CFI-partner ≥3, with which 84.6% of SCD subjects can be correctly identified.
Our results suggest that the CFI, particularly the partner report, appears to be an effective tool for differentiating individuals with SCD, with a cut-off value ≥3. Future research is needed to validate these findings
| If you're submitting a symposium, or a talk that is part of a symposium, is this a junior symposium? | No |
|---|
