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Fibromyalgia (FM) is characterized by chronic widespread pain with muscoloskeletal stiffness and tenderness.
FM patients were investigated with skin biopsy for Small Fiber Neuropathy SFN: Grayston’s metanalysis 2018 concerning 8 studies about FM pooled prevalance of Small Fiber Neuropathy (SFN) (49%).
Electromagnetic hypersensitivity (EHS) is characterized by a variety of no specific symptoms which afflicted individuals attribute to exposure to Electromagnetic field EMF (self - reported).
The study was carried out on 31 subjects:11 with EHS and FM, 10 with EHS and 10 controls. All subjects were administered nine tests: (SGWB), (RSE), (MSPSS), (CD-RISC),(GSE), (LOC), (BAI), (CES- D), (BFQ).
Futhemore, the subjects underwent skin biopsy
Results showed that thin fiber pathology exists in EHS with or without fibromyalgia FM.
MANOVA performed to assess differences between FM – EHS, EHS and control group for SGWB, RSE, MSPSS, CD-RISC, GSE, LOC, CES- D, BAI and BFQ, was significant. The ANOVAs for each dependent variables showed just one significant result for BAI. Post – hoc showed significant differences between FM – EHS, EHS and control group (p < 0.05). For all test the subjects result’s lie under the pathology threasholds.
Furthermore SFN was found in 15 patients showing an epidermal denervatuo whereas 6 patients presented a normal epidermal innervation.: 11 of 11 in the FM-EHS group and 4 of 10 in the EHS group showed SFN.
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