Sep 11 – 13, 2025
Campus Luigi Einaudi
Europe/Rome timezone

TAP-COG: Preliminary validation of a tablet-based neuropsychological battery

Sep 12, 2025, 12:30 PM
1h 45m
Poster Methodology Lunch and poster 2

Speaker

Dr Denise Mellace (University of Milan, Milan, Italy)

Description

Background
As digital health technologies advance, neuropsychological assessment is undergoing a shift toward more standardized, efficient, and accessible formats. Tablet-based solutions enable automated testing, precise response tracking, and remote delivery—expanding opportunities for early cognitive screening. In this context, we developed TAP-COG, a digital battery for cognitive assessment, and present here its preliminary validation.
Methods
The TAP-COG battery, designed for tablet-based use as a progressive web application, was administered to 80 healthy adults (age, 40.75±17.72; education, 15.23±3.2, 58.75% female). The battery includes five subtests: Reaction Time (RT), Go/No-Go, Visual Recognition Test (VRT), Simon Test, and Interference Test. Usability was assessed using the System Usability Scale. Non-parametric analyses were performed to examine construct validity by comparing performances between computerized and paper-based tests and associations with demographic variables.
Results
Correlation analyses revealed moderate positive correlations between RT and Trail Making Test-A (rs=.40, p<.001); Go/No-Go and Stroop (rs=.35, p<.001); VRT accuracy and Immediate Visual Memory test (rs=.57, p<.001). Age was associated with slower reaction times in RT and Go/No-Go (p<.001), and with lower VRT accuracy (p=.009). Education correlated with faster Go/No-Go reaction times (p=.008) and higher VRT accuracy (p=.012). A sex effect was observed only in Go/No-Go (p=.016). Usability was rated from good to excellent by 80% of participants, regardless of age, education, and cognitive efficiency.
Conclusions
This study suggests high perceived acceptability of the TAP-COG battery and provides preliminary support for its construct validity. Further research with larger samples and the establishment of normative data is needed to confirm its clinical applicability.

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Primary author

Dr Denise Mellace (University of Milan, Milan, Italy)

Co-authors

Dr Edoardo Aiello (IRCCS Istituto Auxologico Italiano, Milan, Italy) Dr Roberto Prandin (University of Milan, Milan, Italy) Prof. Sara Marceglia (University of Milan, Milan, Italy) Prof. Barbara Poletti (IRCCS Istituto Auxologico Italiano, Milan, Italy) Dr Carlo Manzoni (University of Milan, Milan, Italy) Dr Angelica De Sandi (Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy) Prof. Gabriella Santangelo (Luigi Vanvitelli University of Campania, Caserta, Italy) Prof. Roberta Ferrucci (University of Milan, Milan, Italy)

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